|
KMID : 0191120200350280257
|
|
Journal of Korean Medical Science
2020 Volume.35 No. 28 p.257 ~ p.257
|
|
|
Acute Kidney Injury and Kidney Damage in COVID-19 Patients
|
|
Na Ki-Ryang
Kim Hae-Ri
Ham Young-Rok
Choi Dae-Eun
Lee Kang-Wook
Moon Jae-Young
Kim Yeon-Sook
Cheon Shin-Hye
Sohn Kyung-Mok
Kim Jung-Ok
Kim Sung-Min
Jeong Hyeong-Seok
Jeon Jae-Wan
|
|
|
Abstract
|
|
|
Background: Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This disease, which is quickly spreading worldwide, has high potential for infection and causes rapid progression of lung lesions, resulting in a high mortality rate. This study aimed to investigate the effects of SARS-CoV-2 infection on renal function in patients with COVID-19.
Methods: From February 21 to April 24, 2020, 66 patients diagnosed with COVID-19 at Chungnam National University Hospital were analyzed; all patients underwent routine urinalysis and were tested for serum creatinine, urine protein to creatinine ratio (PCR), and urine albumin to creatinine ratio (ACR).
Results: Acute kidney injury (AKI) occurred in 3 (4.5%) of the 66 patients, and 1 patient with AKI stage 3 underwent hemodialysis. Upon follow-up, all 3 patients recovered normal renal function. Compared with patients with mild COVID-19, AKI (n = 3) occurred in patients with severe COVID-19, of whom both urine PCR and ACR were markedly increased.
Conclusion: The incidence of AKI was not high in COVID-19 patients. The lower mortality rate in SARS-CoV-2 infection compared with previous Middle East respiratory syndrome and SARS-CoV infections is thought to be associated with a low incidence of dysfunction in organs other than the lungs.
|
|
|
KEYWORD
|
|
|
Coronavirus Disease 2019, COVID-19, Severe Acute Respiratory Syndrome Coronavirus 2, SARS-CoV-2, Acute Kidney Injury, Proteinuria
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
    
|
|